CHART A NEW COURSE
TO ESCAPE CYTOKINE STORM

Groundbreaking immunomodulation technology transforms hyperinflammation into healing

Devastating outcomes signal an urgent need for innovative solutions

Even in 2021, therapeutic options for critically ill patients under attack by a cytokine storm are limited. SeaStar Medical’s Selective Cytopheretic Device (SCD) is a patented, next-level immunomodulator that works with any continuous renal replacement therapy (CRRT) system (and regional citrate anticoagulation) to selectively target hyperactive neutrophils and monocytes. SCD technology won’t just stop the storm, but could potentially reverse the damage.

Neutralize toxic neutrophils and transform monocytes

Neutrophils and monocytes are leukocytes that play a key role in life-threatening hyperinflammation.

The novel SCD technology sequesters and neutralizes activated toxic neutrophils, providing a new therapeutic approach to systemic inflammatory response syndrome.1

By restoring reparative physiology, the SCD can help the body heal—potentially eliminating dialysis dependency and getting patients out of the ICU faster so they can return to their loved ones and daily lives.

Currently, drug treatments for a cytokine storm may differ based on the specific disorder associated with it, and these treatments may not deliver the results your patients need.

Because the SCD is an extracorporeal immunomodulator that uses the body’s immune system to heal, you’re in complete control of an effective adjuvant therapy that can be used without the worry of severe contraindications.

An evidence-based breakthrough

SeaStar Medical is committed to introducing only rigorously researched, clinically validated therapeutic products to the market. And the reason is simple: vital organs and precious lives are at stake. Currently an investigational product, the SCD is a prime example of our high standard of performance.

There are very few therapeutic options available to treat pediatric AKI…these positive [study] results suggest a favorable benefit to risk ratio in the critically ill pediatric population.

Stuart L. Goldstein, MD
Principal Investigator, Pediatric Study

Easy to incorporate into your workflow and treatment paradigm

The SCD can be easily added to your extracorporeal therapies, such as dialysis or continuous renal replacement (CRRT), seamlessly fitting into your workflow. It has been used with other treatments, including IL-6 blockers, corticosteroids and other common treatments, with no or few known contraindications. 

By giving your critically ill patients the potential to eliminate dialysis dependency, get out of the ICU faster, and restore the lives they were so close to losing, the SCD is positioned to become the new standard of care in the ICU.

Get in touch with SeaStar Medical

Intrigued by the promise of the SCD? Want to know more? We’ll be happy to hear from you.

References: 1. Goldstein SL, Askenazi DJ, Basu RK, et al. Use of the Selective Cytopheretic Device in Critically Ill Children. Kidney International Reports. 2020. https://doi.org/10.1016/j.ekir.2020.12.010. 2. Tumlin JA, Galphin CM, Tolwani AJ, et al. A multi-center, randomized, controlled, pivotal study to assess the safety and efficacy of a selective cytopheretic device in patients with acute kidney injury. PLoS One. 2015;10(8):e0132482. PMID: 26244978.

The SCD is an investigational device and is not currently available for sale. Please check back for further updates on device availability in your region.