SeaStar Medical's Industry Lunch Symposium webcast from the AKI & CRRT 2024 Conference

Pathogenic and mechanical triggers of a cytokine storm

viral infection

VIRAL INFECTION

Examples:
SARS-CoV-2, influenza A, dengue virus

bacterial infection

BACTERIAL INFECTION

Examples:
Staphylococcus aureus, Escherichia coli, Francisella tularensis

trauma

TRAUMA

Examples:
Acute lung injury, acute kidney injury, hemorrhagic shock

surgery

SURGERY

Examples:
Surgical AKI, invasive surgery, tissue injury, septic shock

The cytokine storm can exert its lethal effect by damaging multiple organs, including 10-17:

Through organ crosstalk, damaged organs can cause further destruction to other organs (as illustrated by arrows). Note: These are not all the possible morbidities associated with the cytokine storm.